(15 customer reviews)

Anti-Aging Formula, 30 capsules



  • Anti-Aging
  • Detoxifies Brain
  • Improves Memory


  • 1 bottle of 30 Bulletproof Upgraded Aging Formula capsules

$ 167 $ 129


Are you working to reduce everyday stress, fatigue, and brain fog? Do you want your thoughts to be smoother and more productive? Do you want to supercharge your brain for better learning and faster thinking without the side effects of stimulants? That’s a big part of learning to be in the Bulletproof state of high performance. It’s something we strive for every day, always seeking new ways to do more.

After years of testing, Bulletproof is excited to introduce a new substance that has risen above the rest as a safe, effective way to Bulletproof your brain: oxaloacetate, also known as OAA.

Shown to protect neurons in the brain from common environmental toxins, OAA may actually improve day-to-day brain function by improving short-term memory, as well as increasing quality of life.

Oxaloacetate is an anti-aging formula every Bulletproof person should consider for quality and length of life. Here’s why:

  • It’s a nutritional supplement, not a drug. Oxaloacetate is found in many foods, and it’s a critical metabolic compound in your body.
  • In fact, it’s so critical that oxaloacetate is actually required for your body to make energy, to make proteins, and even to make its own fat.
  • When something is so needed for so many major processes that our brains depend on everyday, you can understand our recommendation to try it to support brain health, to clear brain fog, and to optimize clear cognitive potential.


Our oxaloacetate is an extremely high quality product free of impurities, fillers and stabilizers. It is also thermally stabilized, you don’t have to store it at -40 degrees C.

Upgraded Aging Formula vegi-caps are 100%soy-free, gluten-free, sugar-free, and contain no colorants, no flow agents, and no preservatives.

Our Oxaloacetate is in a form that is easily assimilated – PKA studies show it in the bloodstream approximately 30 minutes after ingestion.

Use & Ingredients

Our main recommendation for oxaloacetate is: support brain health, clear brain fog, and optimize clear cognitive potential. There are 250mg of Upgraded Aging Formula in each capsule, and 30 capsules in 1 bottle. 100mg of each capsule is thermally stabilized oxaloacetate, and 150mg is vitamin C.

Shelf Life:

2 years

Note: Vitamin C is not just a filler: it’s a key ingredient. Vitamin C acts as an electron acceptor, stabilizing the oxaloacetate and unlocking its full potential.


If you are 18 years or younger, pregnant or lactating, on medication (including blood pressure medication), have a medical condition, or are allergic to any listed ingredients, please consult your health care practitioner before using this product. Do not use if safety seal is broken or missing.


If you have suffered tramatic head injury or stroke, please consult with your license health care provider before taking this product.

Aging Formula – What does Science and Research Say

Oxaloacetate Gives You The Advantages of Caloric Restriction (without restricting calories)

Oxaloacetate is a calorie restriction mimetic. It takes advantage of the benefits of calorie restriction while saving you from the negatives. In animals, calorie restriction can extend lifespan by up to 50%.

There is little question calorie restriction extends life in animals, but it can cause problems for humans like low body temperature, muscle loss, cognitive dysfunction, and decreased quality of life. This dilemma has led researchers to look for substances that mimic the effects of calorie restriction, while avoiding the side effects.

Oxaloacetate is the most promising substance we’ve yet found. It extends lifespan in worms and rodents by triggering the same effects as caloric restriction. By mimicing caloric restriction without its harmful effects, oxaloacetate has a plethora of health benefits, many of which we are just beginning to understand.

Oxaloacetate is thought to work by protecting neurons from harmful amounts of glutamate, and protecting mitochondria from DNA damage due to environmental toxins. Oxaloacetate may also support health in age-related conditions.

Oxaloacetate Programs Your Genes for Maximum Longevity

Animal models show that oxaloacetate tells genes to keep you alive longer than would normally be possible. Activating the AMPK-FOXO pathways through calorie restriction extends lifespan in worms. In vitro, oxaloacetate can increase NAD+ levels by 50%, which activates the AMPK-FOXO pathways. Oxaloacetate may potentially support an increase lifespan.

Why Your Brain is in Danger (and How Oxaloacetate Can Help)

Oxaloacetate maintains healthy neurons in your brain and nervous system by insuring that there is no toxic build-up of glutamate in your head.(+)

Glutamate is the most common neurotransmitter in your body. Monosodium glutamate (MSG) also raises glutamate levels in the human body. It is needed for learning and memory, but under the wrong conditions, it can kill neurons.

In excess, glutamate excites your brain cells to death, which can lead to serious problems including cognitive decline. In particular, glutamate kills the cells that make myelin, the coating around your nerves that is needed for the creation of white matter.

When everything is working right, glutamate levels in the brain are kept in a fine balance, with just enough being produced to support brain function without causing harm. However, chronic stress impairs glutamate metabolism so that excess glutamate accumulates in the brain.

Over time, excess glutamate can cause mental impairment, sleep problems, and even more stress, all of which impairs glutamate recycling. This becomes a vicious cycle where stress leads to glutamate toxicity, and glutamate toxicity leads to more stress. Oxaloacetate supports healthy glutamate metabolism, supporting appropriate brain function.

Oxaloacetate Protects You From Brain Damage and Supports Your Mitochondria

Oxaloacetate steps in and keeps glutamate from wreaking havoc on your brain. Not only does it reduce glutamate levels, it converts the harmful excess glutamate into fuel for neurons.

Injecting rats with oxaloacetate also reduced glutamate levels and protected neurons after traumatic head injury. This results in improved brain function over the long term. On the flip side, when oxaloacetate metabolism is blocked in animals that suffer a stroke, brain damage is far more severe.

Even though most studies on Oxaloacetate are done in animal studies, Oxaloacetate shows a lot of promise for supporting and maintaining proper neurological function. For our purposes, we use it to clear brain fog that can result from stress and glutamate buildup, and provide neurological support for smoother thought processes and performance. Please remember to consult with your licensed healthcare provider, first, before taking this product if you have had a traumatic head injury or have suffered a stroke.

Supports Your Mitochondria

Damage to mitochondrial DNA is a major contributor to aging and other serious conditions. Loss of brain function is often preceded by a decline in mitochondrial function.

In vitro studies have shown that oxaloacetate protects against mitochondrial DNA damage from environmental toxins. Oxaloacetate also supports your DNA by increasing NAD+ levels in your cells, which shields DNA from free radical damage. In rats, oxaloacetate can reduce mitochondrial damage caused by excitotoxins.

Oxaloacetate has also been shown to increase the protective effects of zinc on human eye cells in a test tube. By supporting your DNA and other tissues, oxaloacetate may reduce your risk of many age-related degenerative conditions.

If you want to learn more about oxaloacetate, check out some of our sources below!


Additional information


15 reviews for Anti-Aging Formula, 30 capsules

  1. Aleena Brecken

    I’ve been taking this supplement for at least a year. Although I would love to take it twice / day, it’s a little pricey for me. Therefore, through trial and error, I determined the best time to take it that works for me. I’ve found that I get the most out of it taking it before bed as part of my “bedtime stack.” I’ve run out of it more than once and each time noticed a difference in the quality and deepness of my sleep.

    Hope this review helps someone else. I take this product mostly for the science behind it and the anti-aging benefits. Additionally, I notice a difference adding it to my nighttime stack, which is a huge win.

  2. Sana Carter

    After taking this for 3 months, I’ve noticed my thoughts are more clearer, organized, and well thought out, and my memory recall improved substantially. I also feel better about life. It’s weird, but great. I highly recommend this one as part of your daily routine!

  3. Raiha Jefferson

    This supplement is amazing! I’ve tried several other supplements, trying to improve my focus and mental clarity, but nothing has been as effective as the Aging Formula. It doesn’t make you feel hyped up or weird in anyway. I just notice that I’m able to focus better at work and get so much more work done than on days I don’t take it. I will be reordering this one.

  4. Rachelle Matthew

    Of all of the Bulletproof products that I have tried, the Aging Formula is one of the products that has the most significant impact on my mental clarity.

  5. Tirna Richard

    The same day I took Oxaloacetate my ability to speak after my brain injury improved noticeably and every day after that I improved obviously to the people around me. Three months down the track my improvement in brain performance continues. My brain injury was caused by accidental chronic Carbon monoxide, LPG and LPG gas exhaust exposure over 5 months from a gas heating and gas hot water system. I notice when i do not take oxaloacetate that my performance suffers, my ability to walk and talk accurately decreases and my muscle spasms increase. Thanks so much for sourceing this quality product Dave and supplying it! thank you to all of you at bulletproof!

  6. Shaira Harley

    I take this supplement every day. There’s awesome evidence to back up this products’ tendency to improve longevity and vitality, which is enough to compel me to take it on a daily basis. Highly recommended.

  7. Bab Rodney

    BP Aging formula makes such a big difference for me in mental alertness and clarity. I’m just sharper and more focused when I take it. I hate running out of this product!! Thank goodness for auto shipping because I won’t run out again.

  8. Cael Russ

    I noticed when I ran out of this product and had not consumed it for a week, I lacked the same focus and mental clarity that I enjoy when I am on it. Definitely noticed a difference.

  9. Ed Roderick

    I just purchased my second bottle of the Anti Aging Formula. This product is incredible. I am very mentally sharp and can focus and remember things with ease. My husband keeps saying I am as sharp as a tack. It works that’s all I can say!

  10. Earl Winston

    I use this daily and find it very very good. Tiny, easy to take pills and lots and lots of vitamin c – something everyone needs this winter. Highly recommended.

  11. Gwen Terrence

    Loving the Aging Formula!!! Noticing better short term memory and clarity. Great product.

  12. Nadin Bailey

    The Aging Formula has given me an instant boost within less than a week – I felt more balanced and even throughout the day. Mental clarity and an overall improved mood were definitely noticeable. Thanks for a great product! I am test-driving all the supplements from UpgradedSelf, as I will begin to study for the CPA exam next year sometime.

  13. Faith William

    This supplement just makes your brain work better. The first few days were more noticeable and after a week, the effects seem sustained, even if I miss a day, in general, better focus, easier word recall and focus.

  14. Ilona Fenton

    I can not live without this supplement! I am 49 years old, work 65 hours per week, minimum, as COO of a company and in my spare time work on my own niche site, play piano and do various outdoor sports including fishing, kayaking, SUPing, etc. What makes this load not only possible, but enjoyable is the way my brain works and my energy level when I am taking Upgrade Brain.

  15. Jamna Everett

    Decided to not take supplement one day…it was the worst day of my recent past! I really had a hard time focusing on my school work. My wife told me to never not take it again and I ordered more. Thanks!

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